And, with the Omicron variant driving a surge in cases, there were multiple Covid-prompted cancellations Off Broadway, as well as in Chicago, Houston, Denver, Los Angeles and other cities.

“Hamilton,” a sold-out juggernaut that had been the top-grossing show on Broadway, cited breakthrough Covid-19 cases in its company as the reason for the cancellation. The show has been dark since Dec. 15 — the matinee went on as scheduled that day, but the evening performance was scrapped — and the first possible next performance is on Dec. 27.

“Hadestown,” a contemporary retelling of the Orpheus and Eurydice myth, also canceled performances until Dec. 27, as did “Dear Evan Hansen,” about a high school student with anxiety, and “MJ,” a new musical about Michael Jackson that is still in previews. And “Aladdin,” which earlier this fall had weathered a 12-day shutdown, announced on Monday that it would be closed until Sunday.

Most shows are still running — there are currently 32 productions on Broadway, and at least two-thirds of them, including long-running hits like “The Lion King,” “Wicked” and “The Phantom of the Opera,” continue to perform. And a strong-selling revival of “The Music Man,” starring Hugh Jackman and Sutton Foster, was set to start previews Monday night.

But sporadic cancellations are now widespread, on Broadway and beyond.

In recent days, many of the Broadway cancellations have been at large-cast productions, for reasons that are not entirely clear. But there are exceptions: On Monday, the Manhattan Theater Club announced that it was delaying its Broadway production of “Skeleton Crew,” a new play by Dominique Morisseau; previews, which had been scheduled to start Tuesday, would instead start on Dec. 27, “due to company members having tested positive” for the virus.